EFFECT OF WEIGHT LOSS INTERVENTION ON DIABETES RISK AND SUBJECTIVE QUALITY OF LIFE

Author(s): SIMKO, G., UVACSEK, M., Institution: HUNGARIAN UNIVERSITY OF SPORTS SCIENCE, Country: HUNGARY, Abstract-ID: 339

INTRODUCTION:
Today, 537 million people worldwide have diabetes, 61 millions of whom live in Europe (IDF Diabetes Atlas, 2021). In Hungary, the number of adult diabetics per 100 inhabitants has tripled in 20 years (KSH 2020). Overweight is a major contributor to T2D. Genetic predisposition contributes to the risk of T2D, but the development of the disease is strongly associated with overweight and lifestyle factors, including diet and inactivity. Low health-related quality of life (HRQoL) is significantly and directly associated with an estimated risk of developing T2D (Väätäinen et al., 2016). Changes in HRQoL are associated with increases in physical activity level (Florez et al., 2012). The aim of our study was to investigate the effect of a 12-week weight loss programme on T2D risk, HRQoL and body composition.
METHODS:
The 12-week lifestyle programme was fulfilled by 30 healthy Hungarian overweight women. Body composition was assessed using the InBody 720 device and diabetes risk was evaluated with the Hungarian version of the Finnish Diabetes Risk Questionnaire. Quality of life scores were assessed using the EQ-5D-5L questionnaire. Statistical analyses were performed using TIBCO Statistica 13.40.14. All statistical tests were performed at 5% significance level.
RESULTS:
The mean age of the participants was 33.4±4.28 years and all of them were overweight or obese. Regarding the risk of T2D we found a significant difference between the baseline and final score (8.36±2.51 vs. 6.96±2.48). There was also a significant change in the mean HRQoL score (73±15.08 vs. 83±11.10). No significant differences were found in body weight (79.16±9.46 kg vs 76.26±9.87 kg) and BMI (28.09±3.25 kg/m2 vs 26.89±3.38 kg/m2) but the number of participants who reached the recommended physical activity (minimum 30 minutes of moderate-intensity activity/day) increased significantly (8 vs 21).
CONCLUSION:
Based on this study, we conclude that the risk of T2D evaluated within 10 years can be modified in a 12-week long weight loss program. Our results suggest that T2D is preventable through lifestyle intervention. Additionally, a 12-week intervention in the areas of nutrition and physical activity can lead to better subjective quality of life promoting healthier behaviors and health-conscious lifestyles.