Author(s): SAWADA, S., LIU, Z., DENG, P., YOSHIHARA, T., NAITO, H., MACHIDA, S., Institution: JUNTENDO UNIVERSITY, Country: JAPAN, Abstract-ID: 2145

INTRODUCTION:
Gait speed is considered as a representative indicator for evaluating physical function in the diagnosis of sarcopenia and frailty [1-3]. Since gait speed measurements require a certain amount of space, a previous study examined the usefulness of five-times sit-to-stand test as a surrogate of gait speed [4]. On the other hand, we reported that 30s chair stand test (CS-30) could be a useful tool for screening sarcopenia in older Japanese people [5]. The aim of this study is to examine the usefulness of CS-30 as a surrogate of gait speed, and to determine the cut-off point as a surrogate for the recommended gait speed cut-off of 1.0m/s for sarcopenia and frailty [2,3].
METHODS:
A total of 1416 Japanese participants aged 65 years and over volunteered to participate in this study (478 men and 938 women, aged 77.2±7.8 years). For gait speed, participants were instructed to walk a 4-10 m course at their usual pace. For CS-30, participants were instructed to complete sit-to-stand trials using a 40-cm high seat without using their arms as many times as possible in 30 s [6]. Correlation analysis, simple regression analysis and ROC analysis were used to determine the usefulness and cut-off point.
RESULTS:
Correlation analysis showed a significant relationship between gait speed and CS-30 (r = 0.62, p < 0.001), and the estimated formula was derived as follows: CS-30 scores = 14.744 × gait speed - 1.0976 (R2=0.38). From this formula, the CS-30 cut-off point for gait speed cut-off of 1.0m/s was estimated to be 14 times. On the other hand, ROC analysis showed that the AUC of the CS-30 for gait speed cut-off of 1.0 m/s definition was 0.88 (p < 0.001), and the optimal CS-30 score was 14 times (sensitivity, 83.8%; specificity, 80.7%).
CONCLUSION:
The results from both simple regression analysis and ROC analysis indicated significant associations and confirmed that the optimal CS-30 cutoff score for definition the gait speed cut-off of 1.0m/s were consistent in 14 times. CS-30 can be a useful surrogate of gait speed for screening of sarcopenia and frailty.
References:
1. Cruz-Jentoft AJ, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing, 2019. 48(1): p.16-31.
2. Chen LK, et al. Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc, 2020. 21(3): p.300-307.
3. Satake S and Arai H. The revised Japanese version of the Cardiovascular Health Study criteria (revised J-CHS criteria). Geriatr Gerontol Int. 2020. 20(10): p.992-993.
4. Nishimura T, et al. Usefulness of chair stand time as a surrogate of gait speed in diagnosing sarcopenia. Geriatr Gerontol Int, 2017. 17(4): p.659-661.
5. Sawada S, et al. The 30-s chair stand test can be a useful tool for screening sarcopenia in elderly Japanese participants. BMC Musculoskelet Disord, 2021. 22(1): 639.
6. Jones CJ, et al. A 30-s chair-stand test as a measure of lower body strength in community-residing older adults. Res Q Exerc Sport, 1999. 70(2): p.113-119.