ECSS Paris 2023: CP-MH31
INTRODUCTION: Obstructive sleep apnea (OSA) is characterized by recurrent upper airway collapse during sleep, leading to serious health consequences, including increased cardiovascular risk and cognitive impairment. Multilevel airway collapse, particularly at the soft palate and tongue base, is common among OSA patients. While oropharyngeal exercises have been proposed as a non-invasive treatment, traditional delivery methods face challenges such as poor adherence due to time constraints and lack of feedback. The efficacy of group-based telerehabilitation for oropharyngeal exercises remains largely unexplored. This study evaluates the effectiveness of group-based telerehabilitation in delivering multilevel oropharyngeal exercises for OSA management. METHODS: A quasi-experimental, two-group design was employed. Thirty-nine participants diagnosed with OSA via polysomnography were enrolled. The telerehabilitation group attended one to two 45-minute online sessions per week, guided by a trainer, while the control group followed conventional instructions. Generalized Estimating Equations (GEE) were used to analyze the interaction effects between group and time on key outcomes, including Apnea-Hypopnea Index (AHI), sleep quality, and tongue muscle strength. RESULTS: Significant interaction effects (p < .05) were observed in AHI, Hypopnea Index (HI), and AHI in supine position (AHI_S), with the telerehabilitation group showing greater reductions compared to the control group. Additionally, the telerehabilitation group exhibited significant improvements in snoring outcomes, tongue strength (depression, lateralization), and tongue endurance across five directions. While BMI, waist, and hip circumference showed no significant changes, a reduction in neck circumference was noted in the telerehabilitation group, possibly due to improved oropharyngeal muscle function. CONCLUSION: Group-based telerehabilitation of multilevel oropharyngeal exercises demonstrates potential as an effective intervention for OSA by improving AHI, sleep-related outcomes, and tongue muscle function. Future studies with larger sample sizes and randomized allocation are recommended to further validate these findings and enhance exercise adherence monitoring.
Read CV JUNHUI ONGECSS Paris 2023: CP-MH31
INTRODUCTION: Chronic kidney disease (CKD) involves irreversible renal dysfunction and is linked to various complications that impair quality-of-life, increase mortality, and reduce exercise capacity. Regular physical activity contributes to overall health, with aerobic exercise particularly enhancing exercise capacity. However, conventional aerobic exercise may increase cardiac workload and hemodynamic stress, posing potential risks for CKD patients. Eccentric cycling (ECC), characterized by lower oxygen and energy demands, provides an alternative for individuals with exercise intolerance, enabling higher-intensity training with reduced hemodynamic stress. This study aimed to compare the effectiveness of ECC and concentric cycling (CON) in improving body composition, cardiopulmonary fitness, and respiratory function in CKD patients. METHODS: This randomized controlled trial, conducted at a single center, included 45 CKD patients assigned to CTL, CON, and ECC groups. The CON and ECC groups underwent 8-week, 24-session cycling programs. The initial exercise intensity was set at 50% of the maximal output (Watts) while maintaining a rating of perceived exertion (RPE) level maintained at 13. Exercise intensity was progressively increased weekly by 5%–10. Outcomes were evaluated through body composition, cardiopulmonary exercise tests, and respiratory function tests (diaphragm ultrasonography, maximum respiratory pressure), assessed at baseline (pre-test), after 1-month exercise (mid-term test) and post-intervention (post-test). RESULTS: The ECC group exhibited a significant group-by-time interaction in body composition compared to the CON and CTL groups, particularly in skeletal muscle mass (CTL vs. ECC: p < 0.001; CON vs. ECC: p < 0.001/slope: CTL: -0.16, CON: -0.267, ECC: 0.343), bilateral upper hand grip strength (CTL vs. ECC: p < 0.001; CON vs. ECC: p < 0.001),and bilateral lower limb knee extensor strength (CTL vs. ECC: p < 0.001; CON vs. ECC: p < 0.001). Regarding functional capacity, both the ECC and CON groups showed improvements in the Timed Up-and-Go and the 6-Minute Walk Test. Notable, the ECC group demonstrated significantly greater diaphragm excursion performance (CTL vs. ECC: p < 0.001; CON vs. ECC: p < 0.001/slope: CTL: -6.037, CON: -8.006, ECC: 1.285). Furthermore, the ECC group reported a higher quality of life, as reflected in the SF-36 Mental Component Summary (MCS) domain. CONCLUSION: Our study is the first to explore the effects of eccentric cycling exercise on body composition and cardiopulmonary fitness with CKD. The results indicate that ECC is a low-effort, high-benefit exercise modality significantly enhancing body composition, cardiopulmonary fitness, and quality of life in CKD patients. Importantly, no adverse effects were reported throughout the study. These results advocate its use as an innovative intervention for this population.
Read CV Yu-Ting HuangECSS Paris 2023: CP-MH31
INTRODUCTION: Anorexia Nervosa (AN) is a psychiatric disorder characterized by a distorted of body image, fear of weight gain and a high rate of chronicity associated with an increased risk of mortality [1]. The overall prevalence of AN is 3.6% in women and 0.3 % in men [2], with peak onset around 15.5 years of age [3]. Recently AN was associated to Neutrophil/Lymphocyte Ratio (NLR), Monocyte/Lymphocyte Ratio (MLR), and Platelet/Lymphocyte Ratio (PLR) serum increase, suggesting a dysfunctional inflammatory response in this population [4,5]. Although Resistance Training (RT) has been explored as a complementary intervention to improve physical and mental well-being in individuals with AN [6], its effect on inflammatory markers remains unknown. Therefore, this study aimed to analyze the effect of 10-week RT program on NLR, LMR and PLR in serum samples from AN patients receiving day hospital care. METHODS: A total of 20 AN patients (22.25±8.6 years; BMI 16.32±6.1 kg/m2) were enrolled and randomly assigned to either exercise (ANE = 10) or control (ANC = 10) groups. Blood samples were drawn at baseline (T0) and after 10-week training (T1) inflammatory markers were measured and NLR, MLR, and PLR ratios were calculated. Physical fitness assessment included body composition analysis using Tanita BC418 MA and circumferences and skinfold thickness measurements were evaluated at T0 and T1. The RT program consisted of a 10-week supervised program (three per week, 50–60 minutes/session), with progressive moderate-to-high intensity training that included exercises for large muscle groups [6]. A non-parametric U Mann-Whitney or a parametric Student’s t-test was performed based on normality tests. RESULTS: A significant time x group effect was found for neutrophil count, NLR, thigh circumference (TC), lean body mass (LBM) and skeletal muscle mass (SMM) (p < 0.05). The ANE group presented significantly lower absolute neutrophil count (p = 0.010) and NLR ratio (p = 0.017) as well as significantly increased TC (p = 0.032), LBM (p = 0.06) and SMM (p = 0.047) after the 10-week exercise intervention. CONCLUSION: Results from this study revealed for the first time RT’s contribution to the improvement of inflammatory markers in AN patients under day-hospital care. In addition to the improvements found in CT, LBM and SMM, these results show underlying positive effects of RT in regulating inflammatory function in AN. References: 1. Hebebrand, J., 2024. 121(5) p.164-174. 2. Galmiche, M., 2019. 109(5) p.1402-1413. 3. Solmi, M., 2022. 27(1) p. 281–295. 4. Zhang R , 2022. 5. Bou Khalil, R., 2021. 6. Fernandez-del-Valle, M., 2014. 47(6) p.601-609.
Read CV Loretta Francesca coscoECSS Paris 2023: CP-MH31