Abstract details
| Abstract-ID: | 1917 |
| Title of the paper: | The Acute Effect of Aerobic, Resistance, and Concurrent Exercise on Dynamic Cerebral Autoregulation in Healthy Young Adults |
| Authors: | Curtin, E., Buys, P., Weston, M., Egaña, M., Gildea, N. |
| Institution: | Trinity College Dublin |
| Department: | Department of Physiology |
| Country: | Ireland |
| Abstract text | INTRODUCTION: The acute effects of resistance (RES), moderate-intensity continuous (MICE), and concurrent (CONE) exercise on dynamic cerebral autoregulation (dCA), as well as potential sex differences in dCA post exercise remains unexplored. This forms an important area of investigation given exercise poses a challenge to dCA and evidence suggests that females have impaired resting dCA compared to males (Labrecque et al., 2019). However, whether this impairment extends post exercise remains unknown. This study aimed to investigate the acute effects of these exercise modalities on dCA in healthy young adults, and to explore potential sex differences therein. METHODS: 12 males (mean±SD, 24±3.6 years) and 14 females (23±2.1 years) volunteered to take part in this study. Participants completed two preliminary and four experimental visits. On visits one and two, participants completed a ramp incremental cycling test to exhaustion and 1 repetition maximum (1RM) test, respectively. Participants then completed four separate experimental trials that were matched for time (30 minutes): sedentary control day (CONT), RES exercise at 70% 1RM, MICE at 90% gas exchange threshold (GET), CONE consisting of RES and MICE. dCA was assessed pre, and 10 minutes post experimental trials using a single sit-to-stand manoeuvre. Middle cerebral artery blood flow velocity (MCAv) was measured via transcranial Doppler ultrasonography and mean arterial pressure (MAP) was measured via finger plethysmography. Baseline MCAv was taken as the last 60 seconds of seated rest. dCA was quantified as the percentage fall in MCAv relative to the percentage fall in MAP upon standing (?%MCAv/?%MAP). dCA responses were analysed using a mixed model ANOVA. RESULTS: Baseline MCAv remained unaffected by condition or time (P>0.05). Females exhibited higher baseline MCAv compared to males (P=0.01). However, there were no significant interactions between condition, time, and sex (P>0.05). The fall in MCAv upon standing was not significantly different 10 minutes post any experimental condition in comparison to pre, except for the RES trial, where the fall in MCAv in both absolute (10.37±4.20 vs 12.89±3.27 cm/s, P=0.01) and relative (16.16±6.11 vs 20.38±5.20%, P=0.01) terms was greater 10 minutes post. For the fall in MAP, there was no main effect of condition or time (P>0.05). No sex differences were reported for the fall in MCAv or MAP (P>0.05). dCA remained unchanged following all experimental conditions (P=0.61). No sex differences in dCA were found pre or 10 minutes post any experimental trial (P=0.17). CONCLUSION: These findings suggest that: (1) dCA remains intact 10 minutes post-RES, MICE, and CONE, suggesting that acute exercise does not alter dCA responses in healthy young adults; and (2) provides evidence of no sex differences in dCA, highlighting that both males and females exhibit similar dCA both before, and 10 minutes post these exercise conditions. |
| Topic: | Health and Fitness |
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